Studies on the biosynthesis of riboflavin; nitrogen metabolism and flavinogenesis in Eremothecium ashbyii.

نویسندگان

  • T W GOODWIN
  • S PENDLINGTON
چکیده

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منابع مشابه

Development of specific experimental systems for flavinogenesis using non-growing cell of Eremothecium ashbyii.

Experimental systems using non-growing cell of Eremothecium ashbyii to elucidate the mechanism of flavinogenesis were established in this paper. 1. It was found that vacuum infiltration of purines for 2, 3 and 5min and moderate shaking of non-growing cell brought about a good reproducibility of the stimulatory effects on flavinogenesis by purines and furthermore, a higher flavinogenesis. 2. The...

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The effects of certain purines and pyrimidines upon the production of riboflavin by Eremothecium ashbyii.

Eremothecium ashbyii is one of a number of organisms which produce considerable amounts of riboflavin, most of which is secreted by the cells into the medium (Guilliermond, 1935). The investigations of Schopfer (1944) and Schopfer and Guilloud (1945) resulted in the development of a synthetic medium for this organism which permitted growth and riboflavin production to occur under chemically def...

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Studies on the synthesis of riboflavin by a mutant yeast, Saccharomyces cerevisiae.

Though the synthesis of riboflavin in large amounts by microorganisms has been encountered, very little is known about the mechani involved in the biosynthesis of this vitamin. A critical examination of the various environmental conditions for different organisms producing this vitamin showed that the optimum conditions for the production of riboflavin varied widely from organism to organism (S...

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Some nutritional requirements for biosynthesis of riboflavin by Eremothecium ashbyii.

Eremothecium ashbyii Guilliermond is a remarkable organism because of its capability of synthesizing relatively large amounts of riboflavin under appropriate conditions. This vitamin is synthesized to a limited extent by a rather wide variety of microorganisms (Pridham, 1952), but those known particularly for their riboflavin producing abilities along with E. a&hbyii are Ashbya gosypi'i (Wicker...

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The utilization of the ureide carbon of adenine in the biosynthesis of riboflavin in Eremothecium ashbyii.

There is considerable evidence that a critical reaction in purine synthesis is the closure of the purine ring by the addition of a “formate” group to 4-amino-5-imidazolecarboxamide ribonucleotide (1). Apparently the “formate” is added as an active intermediate, since formate as such has little effect in stimulating purine synthesis. Indeed, there is a demonstrable difference in the utilization ...

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عنوان ژورنال:
  • The Biochemical journal

دوره 57 4  شماره 

صفحات  -

تاریخ انتشار 1954